Гы. Один из чиновников ВОЗ имеет патент на ГМ вирус свиного гриппа

nedanna

то есть, в принципе, этот вирус достаточно хорошо известен в узких кругах, и о его "новизне", вероятно, вводят в заблуждение.
интересно также обилие "отмененных" статей патента. что там было?
http://pimpinturtle.com/2009/10/31/scientist-who-heads-who-l...
US Patent Application 20090010962 - Genetically Engineered Swine Influenza Virus and Uses Thereof
Claims
1. An attenuated swine influenza virus
comprising a mutation in a swine influenza NS1 gene that diminishes theability of the NS1 gene product to antagonize the cellular interferonresponse, and permits the attenuated virus, at a multiplicity ofinfection of 0.001, to grow to titers between approximately 3 fold toapproximately 7 fold lower than wild-type swine influenza in pig cells,as determined approximately 5 days post-infection when propagated underthe same conditions.
2. The attenuated swine influenza virus of claim 1, wherein the attenuated virus is genetically engineered.
3. The attenuated swine influenza virus of claim 1, wherein the attenuated virus is a mutagenized virus or reassortant.
4. The attenuated swine influenza virus of claim 2, wherein theattenuated virus is a chimeric virus that expresses a heterologoussequence.
5. The attenuated swine influenza virus of claim 2, wherein theattenuated virus is a chimeric virus that expresses a tumor antigen.
6. The attenuated swine influenza virus of claim 2, wherein theattenuated virus is a chimeric virus that expresses an epitope of aforeign pathogen.
7. The attenuated swine influenza virus of claim 1, wherein pig cellsare PK(D1) cells, PK(15) cells, PK13 cells, NSK cells, LLC-PK1 cells,LLC-PK1A cells, ESK-4 cells, ST cells, PT-K75 cells, PK-2a/CL 13 cellsor SJPL cells.
8. (canceled)
9. The attenuated swine influenza virus of claim 2, wherein the mutation is a deletion at the carboxy terminus of the NS1 gene.
10. (canceled)
11. An attenuated swine influenza virus comprising a modified NS1 gene,wherein the attenuated swine influenza virus is TX/98/del 126,TX/98/del 99 or TX/98/del 73.
12. An attenuated swine influenza virus having an altered interferonantagonist phenotype, wherein said virus comprises a mutation in theNS1 gene resulting in a deletion of between the 105 carboxy terminalamino acid residues and the 160 carboxy terminal amino acid residues ofNS1.
13. The attenuated swine influenza virus of claim 12, wherein the virusis attenuated by a mutation in the NS1 gene resulting in a deletion ofall of the amino acid residues of NS1 except amino acid residues 1-95,amino acid residues 1-90, amino acid residues 1-85, amino acid residues1-80, amino acid residues 1-75, amino acid residues 1-73, amino acidresidues 1-70, amino acid residues 1-65, or amino acid residues 1-60,and wherein the amino terminal amino acid is number 1 and the mutationin the NS1 gene confers an altered interferon antagonist phenotype.
14. (canceled)
15. A immunogenic formulation comprising the attenuated swine influenzavirus of claim 1, and a physiologically acceptable excipient.
16. A immunogenic formulation comprising the attenuated swine influenzavirus of claim 11 or 12, and a physiologically acceptable excipient.
17. A pharmaceutical formulation comprising the attenuated swineinfluenza virus of claim 1, and a physiologically acceptable excipient.
18. A pharmaceutical formulation comprising the attenuated swineinfluenza virus of claim 11 or 12, and a physiologically acceptableexcipient.
19-20. (canceled)
21. The immunogenic formulation of claim 15, wherein the attenuated swine influenza virus is genetically engineered.
22. The immunogenic formulation of claim 21, wherein the attenuatedswine influenza virus is a chimeric virus that expresses a heterologoussequence.
23-26. (canceled)
27. The pharmaceutical formulation of claim 17, wherein the attenuated swine influenza virus is genetically engineered.
28-29. (canceled)
30. The pharmaceutical formulation of claim 27, wherein the attenuatedswine influenza virus is a chimeric virus that expresses a tumorantigen.
31. A method for immunizing or inducing an immune response in a pig,comprising administering to said pig an effective amount of theimmunogenic formulation of claim 21.
32. A method for immunizing or inducing an immune response a pig,comprising administering to said pig an effective amount of theimmunogenic formulation of claim 16.
33. A method of treating a swine influenza virus infection in a pig,comprising administering to said pig an effective amount of thepharmaceutical formulation of claim 27.
34. A method of treating a swine influenza virus infection in a pig,comprising administering to said pig an effective amount of thepharmaceutical formulation of claim 18.
35. A method of treating cancer in a pig, comprising administering tosaid pig an effective amount of the pharmaceutical formulation of claim30.
36-40. (canceled)
41. A method for production of an immunogenic formulationcomprising:(a) propagating in a substrate the attenuated swineinfluenza virus of claim 1; and(b) collecting progeny virus,wherein thesubstrate is a cell, cell line or embryonated egg.
42. A method for production of an immunogenic formulationcomprising:(a) propagating in a substrate the attenuated swineinfluenza virus of claim 11 or 12;(b) collecting progeny virus;whereinthe substrate is a cell, cell line or embryonated egg.
43-56. (canceled)
57. A cell containing the attenuated swine influenza virus of claim 1.
58. (canceled)
59. A cell containing the swine influenza virus of claim 11 or 12.
60-69. (canceled)
70. An embryonated egg containing the attenuated swine influenza virus of claim 1.
71-77. (canceled)
Links to scientists who hold the patent:
1. Robert G. Webster (holds also a high position within the WHO) - wikipedia.org
2. Dr. Jürgen A. Richt - immunobiology.iastate.edu
3. Richard J. Webby - stjude.org
4. Peter Palese - mountsinai.org
5. Adolfo García-Sastre - mssm.edu

petrovna

А что в этом такого? Пандемический штамм гриппа ждали уже несколько лет, поэтому естественно все возможные варианты рассматривались.

demiurg

Идиот, тот свиной грипп, который сейчас — это не первый и не единственный свиной грипп. Вообще они почти все изначально свиные.
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